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Dr. Chertkow is a cognitive neurologist whose clinical and research
work both centre around Alzheimer's Disease and dementia. Dr.
Chertkow's field of research is termed "cognitive neuroscience" -
it attempts to understand the brain basis of behaviour using
studies of normal subjects, brain imaging, and testing of individuals
with brain damage. His initial focus was cognitive neuropsychological
investigations of one component of long-term memory, namely
semantic memory. Cognitive testing has been supplemented by
evaluation of brain function itself using PET - positron emission
tomography, along with other brain imaging modalities: functional
Magnetic Resonance Imaging (fMRI), Magnetic Resonance Spectroscopy
(MRS), and Transcranial magnetic stimulation (TMS).
Work in the Memory clinic impressed on Dr. Chertkow the need
for better tools for early diagnosis of AD. He therefore organized
a multidisciplinary team of researchers to look at various means
of diagnosing AD at the initial onset of memory loss. These studies
of patients with Mild Cognitive Impairment (MCI) have proceeded
longitudinally, establishing a set of different approaches to
early diagnosis currently being tested. These include cognitive
testing, brain imaging measures, and biomarkers such as HO-1
(see Dr. Schipper, below).
Dr. Chertkow's is the major Canadian group studying MCI.
- M.D. 1978- University of Western Ontario
- F.R.C.P.(C) 1985- McGill Neurology
- Associate Professor, Dept. of Neurology and Neurosurgery, McGill
- Associate Member, Division of Geriatric Medicine, Dept. of
Medicine
- Co-Director, Jewish General Hospital / McGill Memory Clinic
- Associate Member, School of Human Communication Disorders,
McGill
- Membre actif, Research Centre, Institut Universitaire de Gériatrie
de Montréal
- 1991-President, C5R (Consortium of Canadian Centres for Clinical
Cognitive Research)
SOME RECENT PUBLICATIONS
McKelvey, R., Bergman, H., Stern, J., Rush, C., Zahirney, G., & Chertkow,
H., (1999). Lack of prognostic significance of SPECT abnormalities
in non-demented elderly individuals with memory loss. Canadian
Journal of Neurological Sciences, 26, 23-28. MEDLINE
link to this publication
Whatmough, C., Chertkow, H., Murtha, S., Templeman, D., Babins,
L. & Kelner, N. (2003). The semantic category effect increases
with worsening anomia in Alzheimer’s type dementia.
Brain and Cognition. MEDLINE
link to publication
Chertkow, H., Bergman, H., Schipper, H.M., Gauthier, S., Bouchard,
R., Fontaine, S., & Clarfield, A. M. [2001). Assessment of
suspected dementia. Canadian Journal of Neurological Sciences, 28:
Suppl.1 – S28-S41. MEDLINE
link to this publication
Massoud, F., and Chertkow, H. (2002). Word reading thresholds
in Alzheimer’s Disease and mild memory loss. Alzheimer
disease and Associated Disorders, 16 (No.1), 31-39. MEDLINE
link to this publication
Whatmough, C., Chertkow, H., Murtha, S., Hanratty, K. (2002).
Dissociable brain regions process object meaning and object structure
during picture naming.Neuropsychologia, 40, 174-186. MEDLINE
link to this publication
Chertkow, H. (2002). Mild Cognitive Impairment. Current
Opinion in Neurology, 15, 401-407. MEDLINE
link to this publication
Saumier, D. & Chertkow, H. (2002). Semantic Memory. Current
Neurology and Neuroscience Reports.2(6), 516-522. MEDLINE
link to this publication
Levinoff, E.J., Li, K.Z.H., Murtha, S., & Chertkow, H. (2004).
Selective attention impairments in Alzheimer disease: Evidence
for dissociable components. Neuropsychology.18(3), 580-588. MEDLINE
link to this publication
Whatmough, C., Verret. L. D., Fung, D. & Chertkow, H. (2004).
Common and contrasting areas of activation for abstract and
concrete concepts: An H215O PET study. Journal of Cognitive Neuroscience.
16 (7). 1211-1226. MEDLINE link to this publication
Dwolatzky, T., Whitehead, V., Doniger, G.M., Simon, E.S., Schweiger,
A., Jaffe, D., & Chertkow, H. (2004). Validity of the Mindstreams
computerized cognitive battery for mild cognitive impairment.
Journal of Molecular Neuroscience, 24, 39-50. MEDLINE
link to this publication
Nasreddine, Z. S., Phillips, N. A., Bédirian, V., Charbonneau,
S., Whitehead, V., Collin, I., Cummings, J.L., & Chertkow,
H., (2005) The Montreal Cognitive Assessment, MoCA: A brief screening
tool for Mild Cognitive Impairment. Journal of the American Geriatrics
Society.53 (4), 695-699. MEDLINE link to this
publication
Levinoff, E.J., Saumier , D., & Chertkow, H. (2005). Focused
attention deficits in patients with Alzheimer’s disease
and mild cognitive impairment. Brain and Cognition, 57, (2),
127-130. MEDLINE link to this publication
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